Other classes of non-enzymatic components include vitamins (e.g., ascorbic acid, -tocopherol), enzymatic cofactors (e.g., Coenzyme Q10), nitrogen compounds (e.g., uric acid), carotenoids (e.g., -carotene, lutein), and minerals (e.g., zinc, selenium)
When inhaled, it may lead to swelling of the mouth, runny nose, drowsiness, or chest tightness
Functional gastrointestinal disorders: approach to patients with functional gastrointestinal disorders
When cells are exposed to oxidative and/or electrophilic stress, KEAP1 thiol residues are directly modified, which inactivates the ubiquitin E3 ligase activity of KEAP1-CUL3 complex, leading to stabilization of NRF2